A03-KB106 Development of Bone Strength Prediction Method by Using Multidisciplinary Computational Anatomy with Damage Mechanics

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  • Primary Investigator
    Mitsugu Todo (Kyushu University, Research Institute for Applied Mechanics, Associate Professor)
  • Co-Researcher
    Yasuharu Nakashima (Kyushu University, Faculty of Medical Sciences, Professor)
    Yusuke Matsuura (Chiba University Hospital, Assistant Professor)
    Takaaki Arahira (Fukuoka Dental College, Division of Biomedical Sciences, Assistant Professor)
    Ikuho Yonezawa (Juntendo University, Faculty of Medicine Associate Professor)


In this study, a novel mathematical model is tried to be developed for bone deformation and fracture analysis. The new model will be combined with the finite element method (FEM) to develop an innovative prediction method of bone strength. This study also includes: solid and structural analysis using FEM with hierarchical bone model constructed from medical CT and micro-CT images, mechanical testing using artificial, animal and cadaver bone specimens, and microscopy of deformation and damage mechanisms of the bone samples. Furthermore, new standard for osteoporosis diagnosis will be tried to be established by using the newly developed FEM software of bone strength analysis.

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